Bullet-Shaped Vesicular Stomatitis Virus
In a latest online article in journal Science Ge et al. report a cryo-electron microscopy structure of a model rhabdovirus, a bullet-shaped vesicular stomatitis virus (VSV). Using their structural data they suggest a mechanism of VSV assembly in which the nucleocapsid spirals from the tip to become the helical trunk.
Cryo-EM structure showing the putative cytoplasmic tail of G protein binding to an M subunit through a thin linker. Image credits Science
Proposed mechanism by which the nucleocapsid ribbon generates the virion head, starting with its bullet tip.Image credits Science
Architectural representation of the virion trunk, rendered in 3D animation.
One Response to “Bullet-Shaped Vesicular Stomatitis Virus”
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Hello OzFebruary 11, 2012 at 5:56 pm -
Good move by Elsevier, but company need more than PR efforts to save it's ground. Why so afraid accepting the new reality, open is future.February 11, 2012 at 3:01 am
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Dear Entrepreneur, CXO of unknown start-up with uncertain business model, be grounded and humble. cheersFebruary 10, 2012 at 2:53 am
Bullet-Shaped Vesicular Stomatitis Virus http://bit.ly/cdsy9Y #fisheye