Infographic: Federal funding for basic science

Source LiveScience.com: Science R&D Spending in the Federal Budget. The economics and politics of science.


Obesity behaves like a contagious disease agent

In a latest paper in PLoS Computational Biology Hill et. al suggest a new theoretical framework to study the spread of entities in a social network. Their model is based on a classical disease model.  Inspired from economic models such [...]


Working with next-generation sequencing data – A short primer

Slides from 9th European Conference on Computational Biology tutorial session on working with next-generation data by Thomas Keane and Jan Aerts,


Knowing the data vs relying on it

It is good to know your data. No matter which area you work, there is always an opportunity to make additional gains by closely observing the characteristic and quality of your data. By experimenting and looking carefully at the data [...]


Creating your own JSON Endpoints for Bio Web Services: Basics

Currently major biological databases use the SOAP/WSDL framework to provide the web-services where communication happens through exchange of XML bits. Now in most of programming language you have SOAP/WSDL clients such as SOAP4R and Savon in Ruby, SOAPy, ZSI, SUDS, and soaplib [...]


The missing library for the structural bioinformatics

Recently Hildebrandt et. al published an update on software BALL (Biochemical Algorithms Library ) in journal BMC bioinformatics (use this URL if DOI don’t resolve). BALL is a comprehensive, heavy-weight library for structural bioinformatics with primary focus on rapid and [...]


Things you always wanted to know about learning statistics, but were afraid to ask

Communicating and teaching the fundamentals of statistics without getting caught up in complex mathematics is a big challenge. This may be particularly complicated if you have to teach the probability-statistics to 6-10 year old children. Teachers need a better way [...]


Directory hierarchy tree display

I wanted to add directory hierarchy tree display in README file for my Github projects as it helps to see the organization of the projects in terms of logical units or building blocks. Thanks to Tree package on Ubuntu you [...]


Scale Up or Scale Out: StackOverflow vs Digg

Scalability is a complex engineering issue. Some organizations choose to scale out while others scale up. Vertical scalability is adding more memory and CPUs to a single box, or scaling up. Vertical scalability or scaling up is well suited for [...]


Are You a Data Detective?

A data detective follows PPDAC (Problem, Plan, Data, Analysis, Conclusion) Cycle, aka Statistical Enquiry Cycle for Statistical investigation and empirical problem solving. Problem- Understanding the problem, defining problem, how do we go about answering this question? Plan- What to measure [...]