Archive for the ‘Systems Biology’ Category

SBML: Let the crowdsourcing begin!

Well SBML editors have came out with this nice idea of crowd-sourcing or community sourcing the debugging process of SBML Level 3 by organizing a contest to find the bugs in the L3 Core specification. Here goes the announcement In [...]


What synthetic biology can learn from programming languages

What is synthetic biology? In simple words Synthetic biology is nothing but putting engineering into biology. An engineered genetic toggle switch developed by Tim Gardner and Jim Collins is a good example of how engineering principles are driving the boat [...]


A Meditation on Biological Modeling

No doubt biological modeling is meant for mainstream biologists also, not just for hard core computer scientists or mathematicians. Not every one using the computer knows how transistors work or let say to drive a car you don’t need to [...]


The Systems Architecture of a Bacterial Cell Cycle


SBML Level 3 is arriving

Last Sunday Systems Biology Markup Language (SBML) community has released a draft specification of SBML Level 3 Version 1 Core. Community has been working steadily for quite sometime now to release a modular version of this widely accepted XML format. [...]


Bioinformatics and Systems Biology: Multidisciplinary scientists versus Interdisciplinary scientist

I could be 1 2 3 Same old wine now in new bottle, a debate which bioinformatics community has followed for the years now became a major agenda for systems biology community as well. During recent Systems Biology Inter-DTC Conference [...]


BioPAX or SBML?

Katherine Mejia asked this question on twitter, well just now I want to keep it short, Both BioPAX (Level 3) and SBML (Level 2) can encode signaling pathways, metabolic pathways and regulatory pathways, although SBML can represent finer details. If [...]


Latest Impact Factors for Bioinformatics, Computational Biology and Systems Biology Journals

Thomson Reuters has recently updated Journal Citation Reports(JCR) for year 2008, and as usual I was interested to see that how different bioinformatics, computational biology and systems biology journal performed last year. Despite all criticism and flaws JCR remains only [...]


Gene duplication effects in stickleback nose

rabbit slough sticklebackOriginally uploaded by frenquency In a recent study, published in journal BMC Systems Biology, Sato et al. suggest that an increase in gene dosage resulting from repeated gene duplication may also confer significant, yet unexpected, effect on the [...]


Backup and fault tolerance in systems biology: Striking similarity with Cloud computing

Striking similarity between biological systems and computing paradigms is not new, and in past there have been several attempts to draw an analogy between systems biology and computing systems. For interested readers I will recommend my last post which examine [...]